Follow Buffalo Bills vs San Francisco 49ers live right here. Stream the game in full, track the live score as it moves, and come back for the highlights once Buffalo Bills and San Francisco 49ers are done.
On paper Buffalo Bills and San Francisco 49ers look evenly matched, so execution after the ball is kicked off is everything. The live score and video track each shift in the Buffalo Bills vs San Francisco 49ers battle.
Can't catch it live? After the final whistle we post full Buffalo Bills vs San Francisco 49ers highlights and a final live-score recap, so you can relive the touchdowns, big plays and defensive stands on demand.
Keep this page handy for the Buffalo Bills vs San Francisco 49ers live stream, real-time score and post-game highlights.